Making sure you have a top QB along with a more than capable backup (to help manage and win games during a stretch if necessary) is extremely important. Right there with QB play, OL and DL (DE and EDGE) talent must be stocked. IMO, OL is easier to cultivate trough recruiting, but evaluations must be solid. DL is more difficult and they are costly in the portal, but they are vital.
Then prioritize the other positions in order of need. Maybe you're thin at TE? Maybe there's a need a physical, hard nosed and experienced safety? More speed or a deep threat at WR? A kicker? Those needs will change year to year, but QB, OL, and DL/DE/EDGE must come first.
The last piece of the puzzle is the coaching. With the ability to have unlimited coaches on the practice fields now, there is no excuse not to have the roster covered with top shelf coaches/teachers.
You look at Indiana, and they've unlocked it. I think UGA does a good job with it too, but most of the teams that advanced had at least some combo of the top tier QB/OL/DL and solid coaching. You get all 4, and you're sitting pretty.