Many are processed within the liver, and can affect the liver, which is why so many say if you have a weakened liver, you can't take them.
I'm not going to change your mind about you needing to be tricked or convinced, but it's hard for me not to reply when there is a fundamentally flawed statement. I don't have to be tricked if the nerve block is or isn't working when the dentist is drilling, when my ibuprofen kicks in when my back or hips aren't being agreeable, or when I succumb to general anesthetic before a procedure. I've got a four year old grandkid with a condition. Once he was cleared for a particular med, it did wonders. He had no knowledge of it, wasn't tricked; if he could've been tricked, he'd have been so when his folks were giving him less effective OTC treatments telling him it would make him better.
If you convinced or tricked yourself that ingesting mercury, arsenic or lead (all natural substances) was safe, or even good for you, would you suffer from poisoning or just carry on with your day?